A vaccine created by University of Georgia College of Veterinary Medicine, Center for Vaccines & Immunology researchers to battle multiple life-threatening fungal infections is successful in achieving protective immunity in pre-clinical animal models while also maintaining the biodiversity of the gut microbiome, according to a new study. This is the first study to evaluate a vaccine’s effect on naturally occurring fungal and bacterial communities in the gut, known as the microbiome. The vaccine, called NXT-2, could be the first to protect against and potentially treat pathogenic fungal infections.